Applied Pharmacokinetics & Pharmacodynamics

Applied Pharmacokinetics & Pharmacodynamics

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The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy. This edition includes case studies that apply concepts to actual patient problems. New chapters cover tacrolimus, mycophenolic acid, sirolimus, antipsychotics, and critical evaluation of therapeutic drug monitoring methods. Other new features include more drawings and reference tables and an appendix on outcome studies with therapeutic drug monitoring.According to his family members, he has gone for days without sleep, has very rapid and pressured speech, has had recent extreme credit card spending, and is quite irritable with others, ... Simple routine determinations of lithium concentrations in red blood cells, spinal fluid, and urine have been ... Refinement must include research that shifts from acute treatment to long-term pharmacologic care.

Title:Applied Pharmacokinetics & Pharmacodynamics
Author: Michael E. Burton
Publisher:Lippincott Williams & Wilkins - 2006

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