Genetic Predisposition to Cancer, 2Ed

Genetic Predisposition to Cancer, 2Ed

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Over the last 20 years it has become increasingly apparent that the occurrence of many cancers can have an inherited basis. This book examines the principles underlying genetic predisposition to cancer and will be relevant to practising oncologists, geneticists and other professionals interested in this rapidly expanding field. Coverage is comprehensive, taking the reader from an introduction to genetic predisposition, through a discussion of the molecular biology and statistical techniques involved in the identification and characterisation of predisposition genes, to a consideration of heritable cancer syndromes, and encompasses both rare and common cancers. The text also features a discussion of cancer risk assessment, genetic counselling issues, genetic screening and cancer management options, and a consideration of the associated ethical and psychological issues. Building on the reputation of the previous edition, and to reflect the rapid advances in the field since its publication, the contents of the second edition have been thoroughly updated and include discussion of many newly identified cancer genes. In particular, the book features new chapters added on the biological basis of cancer predisposition, population-based studies of susceptibility, and evaluation of management strategies for individuals at increased cancer risk.... Research Fellow, Department of Oncology, University of Cambridge, Strangeways Research Laboratories, Cambridge, UK Bruce AJ Ponder PhD FRCP FRCPath FMedSci FRS Cancer Research UK Professor of Oncology; and Co-Director, anbsp;...

Title:Genetic Predisposition to Cancer, 2Ed
Author: Ros Eng, Douglas Easton, Bruce Ponder, Charis Eng
Publisher:CRC Press - 2004-08-27

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